| The effect of a cryotherapy gel wrap on the microcirculation of skin affected by chronic venous disorders. | |
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MedLine Citation:
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PMID: 21592186 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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kelechi t.j., mueller m., zapka j.g. & king d.e. (2011) The effect of a cryotherapy gel wrap on the microcirculation of skin affected by chronic venous disorders. Journal of Advanced Nursing. doi: 10.1111/j.1365-2648.2011.05680.x ABSTRACT: Aim. The aim of this randomized clinical trial was to investigate a cryotherapy (cooling) gel wrap applied to lower leg skin affected by chronic venous disorders to determine whether therapeutic cooling improves skin microcirculation. Background. Chronic venous disorders are under-recognized vascular health problems that result in severe skin damage and ulcerations of the lower legs. Impaired skin microcirculation contributes to venous leg ulcer development, thus new prevention therapies should address the microcirculation to prevent venous leg ulcers. Methods. Sixty participants (n = 30 per group) were randomized to receive one of two daily 30-minute interventions for four weeks. The treatment group applied the cryotherapy gel wrap around the affected lower leg skin, or compression and elevated the legs on a special pillow each evening at bedtime. The standard care group wore compression and elevated the legs only. Laboratory pre- and post-measures included microcirculation measures of skin temperature with a thermistor, blood flow with a laser Doppler flowmeter, and venous refill time with a photoplethysmograph. Data were collected between 2008 2009 and analysed using descriptive statistics, paired t-tests or Wilcoxon signed ranks tests, logistic regression analyses, and mixed model analyses. Results. Fifty-seven participants (treatment = 28; standard care = 29) completed the study. The mean age was 62 years, 70% female, 50% African American. In the final adjusted model, there was a statistically significant decrease in blood flow between the two groups (-6.2[-11.8; -0.6], P = 0.03). No statistically significant differences were noted in temperature or venous refill time. Conclusion. Study findings suggest that cryotherapy improves blood flow by slowing movement within the microcirculation and thus might potentially provide a therapeutic benefit to prevent leg ulcers. |
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Authors:
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Teresa J Kelechi; Martina Mueller; Jane G Zapka; Dana E King |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-19 |
Journal Detail:
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Title: Journal of advanced nursing Volume: - ISSN: 1365-2648 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7609811 Medline TA: J Adv Nurs Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Blackwell Publishing Ltd. |
Affiliation:
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Teresa J. Kelechi PhD RN Associate Professor College of Nursing, Medical University of South Carolina, Charleston, USA Martina Mueller PhD Assistant Professor Biostatistics and Bioinformatics, College of Nursing, Medical University of South Carolina, Charleston, USA Jane G. Zapka ScD Professor Biostatistics and Bioepidemiology, College of Nursing, Medical University of South Carolina, Charleston, USA Dana E. King MD Professor Department of Family Medicine, Medical University of South Carolina, Charleston, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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