Document Detail


The effect of coronary angioplasty on superoxide anion generation and lipid peroxidation. Propriety of pharmacological intervention.
MedLine Citation:
PMID:  8688889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In patients with unstable angina pectoris, subjected (n = 20) or not subjected (n = 12) to percutaneous transluminal coronary angioplasty (PTCA), baseline superoxide anion (O.2-) generation by neutrophils in the coronary sinus blood was significantly higher than that found in the basilic vein blood of control healthy subjects (n = 12). During reperfusion following effective PTCA, neutrophil counts in the coronary sinus blood tended to decrease, an effect accompanied by a significant decrease in the neutrophil O.2- generation and enhancement of blood plasma lipid peroxidation as reflected by increased malonyldialdehyde concentrations.
Authors:
J Kowalski; L Pawlicki; M Kośmider; M Skłodowska; J Gromadzińska; J Kedziora; M Luciak; J Błaszczyk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Polish journal of pharmacology     Volume:  47     ISSN:  1230-6002     ISO Abbreviation:  Pol J Pharmacol     Publication Date:    1995 Mar-Apr
Date Detail:
Created Date:  1996-08-29     Completed Date:  1996-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9313882     Medline TA:  Pol J Pharmacol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Military Medical Academy, Lódź, Poland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Angina, Unstable / blood*,  therapy
Angioplasty, Transluminal, Percutaneous Coronary*
Female
Humans
Lipid Peroxidation*
Male
Middle Aged
Superoxides / metabolism*
Chemical
Reg. No./Substance:
11062-77-4/Superoxides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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