Document Detail


The effect of cinnamaldehyde on the growth and the morphology of Candida albicans.
MedLine Citation:
PMID:  23325549     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We examined the viability and morphology of Candida albicans under experimental conditions after treatment with varying concentrations of cinnamaldehyde, the major component of cassia (Cinnamomum cassia), using XTT assay, fluorescent microscopy, scanning electron microscopy, and thin-section electron microscopy. At 10 μg/ml level, cinnamaldehyde inhibited mycelial growth, but did not affect the growth of yeast cells, metabolic activity, cell shape, or the ultrastructure of the cells. At 40 μg/ml level, cinnamaldehyde showed fungicidal activity accompanied by alteration of the membrane and interior of Candida cells. These findings indicate that cinnamaldehyde has both fungistatic and fungicidal activities against C. albicans and affects the structure of the cells.
Authors:
Yuuki Taguchi; Yayoi Hasumi; Shigeru Abe; Yayoi Nishiyama
Related Documents :
24617039 - Location of proliferating cell nuclear antigen and p53 protein in human first trimester...
23724999 - The genetics of hair cell development and regeneration.
23998069 - The role of immunohistochemistry in the analysis of the spectrum of small round cell tu...
24347159 - Aqueous extract of crataegus azarolus protects against dna damage in human lymphoblast ...
24241959 - Part ii-mechanism of adaptation: a549 cells adapt to high concentration of nitric oxide...
21074249 - Expression of claudin-1 and -11 in immature and mature pheasant (phasianus colchicus) t...
24617039 - Location of proliferating cell nuclear antigen and p53 protein in human first trimester...
122449 - Endocrine regulation of reproductive development and function in the male.
23724999 - The genetics of hair cell development and regeneration.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-17
Journal Detail:
Title:  Medical molecular morphology     Volume:  -     ISSN:  1860-1499     ISO Abbreviation:  Med Mol Morphol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239023     Medline TA:  Med Mol Morphol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Research and Product Development Division, S&B Foods Inc., 38-8 Miyamoto-cho, Itabashiku, Tokyo, 174-8651, Japan, yuuki_taguchi@sbfoods.co.jp.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Boosting signals in gene-based association studies via efficient SNP selection.
Next Document:  Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of l...