Document Detail

The effect of cigarette smoking on urinary hippuric acid concentration in Thai workers with occupational exposure to toluene.
MedLine Citation:
PMID:  12188417     Owner:  NLM     Status:  MEDLINE    
Urine hippuric acid determination is helpful for monitoring of group of workers at risk for exposure to toluene. However, some problems about the external source of variation are mentioned. Some studies have indicated that smoking is an important external source of variation for determination of urine hippuric acid level while the others stated the opposite findings. This study was conducted in an attempt to study the difference of urine hippuric acid between smoking and non smoking subjects in a press workers group. Urine samples were obtained from 46 workers (all male) who worked as press workers in the same press factory in Bangkok. The individuals were classified as control (non smoking, N = 26) and experimental (smoking, N = 20) according to their smoking. All samples were analyzed for hippuric acid level. The average urine hippuric acid level for the control were (0.35 +/- 0.31 mg/gCr) and experimental group (0.40 + 0.45 mg/gCr) were respectively. No significant difference was found between urine hippuric acid level between both groups. The data from the current study indicates that smoking does not influence the urinary hippuric acid levels in this study group.
Viroj Wiwanitkit; Jamsai Suwansaksri; Suriya Srita; Anucha Fongsoongnern
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  85 Suppl 1     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-08-21     Completed Date:  2002-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  S236-40     Citation Subset:  IM    
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Biological Markers / analysis
Case-Control Studies
Hippurates / metabolism,  urine*
Middle Aged
Occupational Exposure / adverse effects*
Occupational Health
Reference Values
Regression Analysis
Risk Assessment
Sampling Studies
Sensitivity and Specificity
Smoking / adverse effects*
Toluene / adverse effects*
Reg. No./Substance:
0/Biological Markers; 0/Hippurates; 108-88-3/Toluene; 495-69-2/hippuric acid

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