Document Detail

The effect of cerebrospinal fluid pressure on the size of drainage pathways.
MedLine Citation:
PMID:  945514     Owner:  NLM     Status:  MEDLINE    
The cerebrospinal fluid drainage pathways were studied using labeled molecules of different sizes. Following determination of the limiting size, the cerebrospinal fluid pressure was raised above the normal range and changes in transfer were measured. These data show that molecules smaller than the limiting size will transfer at an increased rate in response to elevated pressures. Larger molecules did not demonstrate an increased transfer with raised cerebrospinal fluid pressures, suggesting that the pathways did not enlarge.
A E James; J G McComb; J Christian; H Davson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  26     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-08-23     Completed Date:  1976-08-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  659-63     Citation Subset:  IM    
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MeSH Terms
Cerebrospinal Fluid / physiology*
Intracranial Pressure*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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