| The effect of calcium phosphate implant coating on osteoconduction. | |
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MedLine Citation:
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PMID: 11740476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to determine whether a calcium phosphate (CaP) coating would have a significant impact on osteoconduction. Study Design: In this investigation, porous-surfaced titanium alloy (Ti-6Al-4V) implants were prepared with or without the addition of a thin surface layer of CaP applied by means of sol-gel coating and implanted into the tibiae of 16 rabbits. Implant sites were allowed to heal for 2 weeks, after which specimens were retrieved for morphometric assessment by using backscatter scanning electron microscopy and the Bioquant Image Analyzer. RESULTS: The absolute contact length was significantly (P <.01) higher for CaP-coated implants (1.18 mm) than for the noncoated implants (0.74 mm), as were the contact length fraction (40.4% vs 27.0%; P <.01) and the straight-line bone growth (1.19 mm vs 1.04 mm; P <.01). CONCLUSION: On the basis of the findings in this study, the addition of a thin layer of CaP to the implant promotes accelerated bone healing around porous-surfaced implants-even after only 2 weeks of initial healing. |
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Authors:
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C Yang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics Volume: 92 ISSN: 1079-2104 ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2001-12-12 Completed Date: 2002-03-04 Revised Date: 2013-04-05 |
Medline Journal Info:
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Nlm Unique ID: 9508562 Medline TA: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Country: United States |
Other Details:
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Languages: eng Pagination: 606-9 Citation Subset: D; IM |
Affiliation:
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Stomatology Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Animals Calcium Phosphates / pharmacology* Coated Materials, Biocompatible / pharmacology* Implants, Experimental* Male Models, Animal Osteogenesis / drug effects* Rabbits Statistics, Nonparametric Tibia / surgery Titanium |
| Chemical | |
Reg. No./Substance:
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0/Calcium Phosphates; 0/Coated Materials, Biocompatible; 0/alpha-tricalcium phosphate; 0/monocalcium phosphate; 0/tetracalcium phosphate; 12743-70-3/titanium alloy (TiAl6V4); 7440-32-6/Titanium; 97Z1WI3NDX/calcium phosphate; L11K75P92J/dicalcium phosphate anhydrous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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