Document Detail

The effect of calcium consumption on iron absorption and iron status.
MedLine Citation:
PMID:  12455225     Owner:  NLM     Status:  MEDLINE    
Recent increases in recommended calcium intakes recognize the important role of calcium in skeletal health, but many Americans, especially women, consume far less than recommended amounts. A potential drawback to encouraging increased calcium intake is suggested by the extensive literature showing an adverse effect of high calcium intake on dietary iron absorption, at least in short, highly controlled, experimental studies. However, the applicability of short-term studies involving test meals to long-term iron absorption and iron status is limited given the variety of foods and food combinations in self-selected diets and the ability of individuals to adapt to reduced iron intake. In general, studies of whole diets and studies conducted over several weeks tend to show no effect of increased calcium intake on iron absorption. In addition, experimental studies of calcium and iron status measures such as serum ferritin show no long-term effect of calcium supplementation on iron status. Prevention and treatment of iron deficiency should emphasize adequate consumption of iron-rich foods and, when indicated, the use of iron supplements. Recommended calcium intakes are important for skeletal health and do not appear to increase the risk for iron deficiency in healthy people.
Susan S Harris
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Nutrition in clinical care : an official publication of Tufts University     Volume:  5     ISSN:  1096-6781     ISO Abbreviation:  Nutr Clin Care     Publication Date:    2002 Sep-Oct
Date Detail:
Created Date:  2002-11-28     Completed Date:  2003-03-11     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9809674     Medline TA:  Nutr Clin Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  231-5     Citation Subset:  IM    
New England Research Institutes.
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MeSH Terms
Calcium, Dietary / administration & dosage*,  adverse effects
Dietary Supplements
Intestinal Absorption
Iron / blood*,  deficiency
Iron, Dietary / pharmacokinetics*
Nutritional Status
Nutritive Value
Reg. No./Substance:
0/Calcium, Dietary; 0/Iron, Dietary; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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