| The effect of bopindolol on lipids and platelet aggregation. | |
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MedLine Citation:
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PMID: 3229118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An open ambulatory study was performed to assess the effect of bopindolol in 19 hypertensive patients (W.H.O. stage I-II). A statistically significant decrease in systolic and diastolic pressure as well as heart rate (never below 60 beats per minute) was demonstrated. No undesirable subjective side-effects of the drug were reported. Compared with the serum concentrations after placebo, a decrease in all low-density fractions was observed after 12 months. The total cholesterol/HDL cholesterol ratio did not deteriorate and the apolipoprotein A/apolipoprotein B ratio increased. The values of triacylglycerols during 8 months of therapy did not exceed initial serum concentrations following placebo administration. Patients treated with bopindolol exhibited decreased platelet aggregation due to collagen. |
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Authors:
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E Pintérová; J Kacerovský; Z Zadák; J Malý; V Pidrman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cor et vasa Volume: 30 ISSN: 0010-8650 ISO Abbreviation: Cor Vasa Publication Date: 1988 |
Date Detail:
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Created Date: 1989-04-14 Completed Date: 1989-04-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372614 Medline TA: Cor Vasa Country: CZECHOSLOVAKIA |
Other Details:
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Languages: eng Pagination: 352-60 Citation Subset: IM |
Affiliation:
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2nd Department of Medicine, Teaching Hospital J.E. Purkynĕ Military Research, Hradec Králové, Czechoslovakia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Antihypertensive Agents / pharmacology*, therapeutic use Heart Rate / drug effects Humans Lipids / blood* Middle Aged Pindolol / analogs & derivatives*, pharmacology, therapeutic use Platelet Aggregation / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 0/Lipids; 13523-86-9/Pindolol; 69010-88-4/bopindolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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