| The effect of beta blockade on the reaction of pressure and mesenteric flow to biogenic amines in normal and X-irradiated rats. | |
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MedLine Citation:
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PMID: 6111139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A beta-blocker, propranolol, was infused to control and irradiated rats the 1st and 3rd day after 2-kR X-ray irradiation. Blood pressure and mesenteric blood flow were recorded during infusion of biogenic amines (noradrenaline, dopamine, serotonin, acetylcholine and histamine). After beta-blockade, there was intensified increase in pressure and decrease in flow with increased overshoot after infusion of noradrenaline, no effect on the increase in pressure and flow after dopamine, but an enhanced increase in pressure and decrease in flow after serotonin. No effect on the decrease in pressure and flow was seen after acetylcholine, and a greater decrease in pressure and flow, after histamine. Irradiation altered the vascular reactivity, mainly for noradrenaline, serotonin and histamine. |
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Authors:
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R Timmermans; G B Gerber |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Strahlentherapie Volume: 157 ISSN: 0039-2073 ISO Abbreviation: Strahlentherapie Publication Date: 1981 Mar |
Date Detail:
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Created Date: 1981-05-28 Completed Date: 1981-05-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1260024 Medline TA: Strahlentherapie Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 208-12 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetylcholine
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pharmacology Adrenergic beta-Antagonists / pharmacology* Animals Blood Pressure / drug effects* Dopamine / pharmacology Histamine / pharmacology Mesenteric Arteries / drug effects*, radiation effects Norepinephrine / pharmacology Propranolol / pharmacology* Radiation Effects* Rats Regional Blood Flow / drug effects Serotonin / pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 50-67-9/Serotonin; 51-41-2/Norepinephrine; 51-45-6/Histamine; 51-84-3/Acetylcholine; 525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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