Document Detail

The effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis.
MedLine Citation:
PMID:  1102149     Owner:  NLM     Status:  MEDLINE    
Nasal resistance to air flow has been used to evaluate the effect of beclomethasone dipropionate aerosol on allergen induced nasal stenosis. Sixteen patients with allergic rhinitis due to pollen were investigated in a randomized double-blind cross-over study with beclomethasone dipropionate aerosol and placebo aerosol. Only patients reacting to challenge were chosen. The study was carried out in the pollen-free season. After 1 week on either active or placebo aerosol a basic resistance value was determined followed by allergen challenge. Nasal resistance was determined 15 min and 7 hr after challenge. The aerosols were changed and after another week the procedure was repeated. There was significant preference (P less than 0.01) for beclomethasone dipropionate aerosol.
J S Vilsvik; A O Jennssen; R Walstad
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical allergy     Volume:  5     ISSN:  0009-9090     ISO Abbreviation:  Clin. Allergy     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1976-01-30     Completed Date:  1976-01-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0311172     Medline TA:  Clin Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  IM    
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MeSH Terms
Administration, Intranasal
Airway Resistance / drug effects
Allergens / administration & dosage*
Beclomethasone / therapeutic use*
Clinical Trials as Topic
Constriction, Pathologic
Methylprednisolone / analogs & derivatives*
Nasal Mucosa / drug effects*
Reg. No./Substance:
0/Aerosols; 0/Allergens; 4419-39-0/Beclomethasone; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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