Document Detail


The effect of aspirin on peripheral haemodynamic changes following submaximal exercise in normal volunteers.
MedLine Citation:
PMID:  6467268     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight normal healthy volunteers participated in a study to determine the effect of 1800 mg of aspirin on the peripheral haemodynamic changes that occur following upright exercise. Aspirin reduced the extent of calf hyperaemia (p less than 0.05) and accentuated the reduction in forearm blood flow (p less than 0.05) following exercise. It had no effect on either calf or forearm blood flow at rest. These results indicate that aspirin, possibly by inhibiting prostacyclin production, modifies the circulatory changes following upright exercise.
Authors:
A J Cowley; K Stainer; J M Rowley; S P Hanley
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular research     Volume:  18     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-10-16     Completed Date:  1984-10-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  511-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aspirin / pharmacology*
Forearm / blood supply*
Humans
Leg / blood supply*
Male
Physical Exertion*
Regional Blood Flow / drug effects
Time Factors
Chemical
Reg. No./Substance:
50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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