| The effect of areca nut on salivary and selected oral microorganisms. | |
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MedLine Citation:
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PMID: 9147124 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to investigate the effect on the growth of salivary and selected oral microorganisms of areca nut, aqueous extracts of the nut, its major alkaloid arecoline and the components tannic acid and catechin of its tannin fraction. The antibacterial properties of the above were tested on Streptococcus mutans, Streptococcus salivarius, Candida albicans and Fusobacterium nucleatum and, as a control, Staphylococcus aureus. This was followed by investigating its effect on salivary organisms cultured from the saliva after chewing boiled areca nut. Extracts inhibited the growth of the selected organisms in a concentration dependent manner, baked and boiled nuts being significantly more potent than raw nut. Growth of C. albicans was the least affected by the nut extracts. Tannic acid was strongly antibacterial but not catechin or arecoline. No antibacterial effect could be demonstrated on salivary organisms after chewing the nut for 5 minutes but exposure of saliva to the cud for 1 hour caused a significant depression of bacterial growth. It is concluded that the hydrolysable tannins in the tannin fraction, which include tannic acid, are responsible for the antibacterial properties of the nut and that prolonged intraoral exposure to the nut can suppress bacteria in the mouth. |
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Authors:
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C M de Miranda; C W van Wyk; P van der Biji; N J Basson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International dental journal Volume: 46 ISSN: 0020-6539 ISO Abbreviation: Int Dent J Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1997-07-03 Completed Date: 1997-07-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374714 Medline TA: Int Dent J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 350-6 Citation Subset: D; IM |
Affiliation:
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University of Stellenbosch, Tygerberg, South Africa. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Anti-Bacterial Agents Anti-Infective Agents / administration & dosage, pharmacology Areca* Arecoline / administration & dosage, pharmacology Astringents / administration & dosage, pharmacology Candida albicans / drug effects*, growth & development Catechin / administration & dosage, pharmacology Cookery Dose-Response Relationship, Drug Fusobacterium nucleatum / drug effects*, growth & development Humans Hydrolysis Hydrolyzable Tannins / administration & dosage, pharmacology Mastication Mouth / microbiology* Plant Extracts / pharmacology* Plants, Medicinal* Saliva / microbiology* Staphylococcus aureus / drug effects, growth & development Streptococcus / drug effects*, growth & development Streptococcus mutans / drug effects*, growth & development |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Infective Agents; 0/Astringents; 0/Hydrolyzable Tannins; 0/Plant Extracts; 154-23-4/Catechin; 63-75-2/Arecoline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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