| The effect of an antimicrobial releasing varnish on root demineralisation in situ. The influence of the demineralisation period. | |
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MedLine Citation:
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PMID: 1864854 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Caries in exposed root surfaces is becoming a significant problem in dentistry. Varnish applications have interesting preventive possibilities against root caries. The effect of such a varnish, containing two antimicrobials, was studied on the demineralisation of roots with a twofold aim. Firstly, the efficacy of the varnish was investigated in situ as a function of the demineralisation period. Ten participants wore sound intact roots treated with the varnish in an intra oral appliance for 2, 4 and 6 weeks. Secondly, the effect of the varnish on root demineralisation after removal of the varnish was measured. The results showed that the reduction, in demineralization of about 80% after 2 weeks, decreased in magnitude with the length of the in situ demineralisation period. After 4 weeks there was no longer statistically significant difference compared with untreated roots. The acid attack by plaque was, however, substantial in this model; after 6 weeks in situ untreated roots were so strongly demineralised that microradiography was no longer possible anymore. In the second experiment in which the varnish was removed 2 days after application there was a trend toward a reduction of about 30% in root demineralisation after 2 weeks. This was not statistically significant when compared with no application. |
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Authors:
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E D Huizinga; J Arends |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal de biologie buccale Volume: 19 ISSN: 0301-3952 ISO Abbreviation: J Biol Buccale Publication Date: 1991 Mar |
Date Detail:
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Created Date: 1991-09-11 Completed Date: 1991-09-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0400336 Medline TA: J Biol Buccale Country: FRANCE |
Other Details:
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Languages: eng Pagination: 29-33 Citation Subset: D; IM |
Affiliation:
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Laboratory for Materia Technica, University of Groningen, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Chlorhexidine / administration & dosage, therapeutic use* Dental Caries / metabolism, physiopathology* Dentin / chemistry, drug effects Dentin Solubility / drug effects Female Humans Male Middle Aged Minerals / chemistry Paint Thymol / administration & dosage, therapeutic use* Time Factors Tooth Root / chemistry, drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Minerals; 55-56-1/Chlorhexidine; 89-83-8/Thymol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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