Document Detail


The effect of anti-immunoglobulin antibodies of Fc rosettes.
MedLine Citation:
PMID:  1084014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study demonstrated that Fc rosettes detected by antibody-labeled bovine erythrocytes can be inhibited by immune complexes of rabbit IgG (b4 allotype) and anti-b4 IgG, thus showing that these complexes effectively compete for the receptor for erythrocyte-antibody rosettes. Incubation of mouse lymphocytes with goat F(ab')2 anti-mouse IgG did not inhibit Fc rosettes. When immunoglobulin on murine and human B lymphocytes was redistributed in a polar cap on the membrane by interaction with anti-immunoglobulin antibodies, the number of Fc rosettes after 'capping' was unchanged; most of the indicator erythrocytes, however, were distributed in a cap as well. This erythrocyte cap was superimposed on the immunoglobulin cap.
Authors:
P H Krammer; B Pernis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of immunology     Volume:  5     ISSN:  0300-9475     ISO Abbreviation:  Scand. J. Immunol.     Publication Date:  1976  
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0323767     Medline TA:  Scand J Immunol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  199-204     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibodies, Anti-Idiotypic*
Antigen-Antibody Complex
Erythrocytes / immunology*
Immune Adherence Reaction*
Immunization
Immunoglobulin Fab Fragments
Immunoglobulin Fc Fragments*
Immunoglobulin G
Lymphocytes / immunology*
Mice
Mice, Inbred AKR
Mice, Inbred CBA
Temperature
Chemical
Reg. No./Substance:
0/Antibodies, Anti-Idiotypic; 0/Antigen-Antibody Complex; 0/Immunoglobulin Fab Fragments; 0/Immunoglobulin Fc Fragments; 0/Immunoglobulin G

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