Document Detail

The effect of angiotensin receptor blockers for preventing atrial fibrillation.
MedLine Citation:
PMID:  17686377     Owner:  NLM     Status:  MEDLINE    
Atrial fibrillation is the most common sustained cardiac arrhythmia in clinical practice, and causes significant burden to patients and health care systems. Clinicians treat existing atrial fibrillation with anticoagulation and/or drugs that utilize either a rate or rhythm control strategy. It remains unclear how best to reduce cardiovascular morbidity and mortality in this population. Prevention of atrial fibrillation using angiotensin receptor blockers, which affect ion currents and refractoriness in atrial myocytes, regress or prevent atrial fibrosis, decrease left atrial size, regress left ventricular hypertrophy, modulate sympathetic nerve activity, reduce inflammation, and reduce blood pressure, may become an important and desirable alternative.
Kristian Wachtell; Richard B Devereux; And Paulette A Lyle
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current hypertension reports     Volume:  9     ISSN:  1522-6417     ISO Abbreviation:  Curr. Hypertens. Rep.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-09     Completed Date:  2008-03-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888982     Medline TA:  Curr Hypertens Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-83     Citation Subset:  IM    
Department of Cardiology B2142, Rigshospitalet, The Heart Center, 9 Blegdamsvej, DK-2100 Copenhagen, Denmark.
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MeSH Terms
Angiotensin II Type 1 Receptor Blockers / pharmacology*,  therapeutic use*
Atrial Fibrillation / epidemiology,  prevention & control*
Primary Prevention / methods*
Risk Factors
Reg. No./Substance:
0/Angiotensin II Type 1 Receptor Blockers

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