Document Detail

The effect of anemia on mortality in indigent patients with mild-to-moderate chronic heart failure.
MedLine Citation:
PMID:  16596040     Owner:  NLM     Status:  MEDLINE    
Anemia has been described as an independent predictor of death in patients with chronic heart failure. Little is known, however, about the significance of anemia in heart failure patients with severely depressed socioeconomic backgrounds who receive comprehensive care in a heart failure management program. The impact of anemia on mortality was investigated in 410 indigent chronic heart failure patients, the majority of whom were in New York Heart Association functional class I-III and were treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and beta blockers at maximally tolerated doses. Anemia was present in 28% of patients. In an adjusted Cox analysis, anemia was strongly associated with mortality, but only in men: hazard ratio, 2.54; 95% confidence interval, 1.31-4.93; p = 0.006. The investigators conclude that anemia in this population is common and that, for men, the relative risk increase associated with anemia is high.
Kathy Hebert; Ron Horswell; Lee Arcement; Joshua Hare; Lynne Stevenson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  12     ISSN:  1527-5299     ISO Abbreviation:  Congest Heart Fail     Publication Date:    2006 Mar-Apr
Date Detail:
Created Date:  2006-04-05     Completed Date:  2006-06-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  75-9     Citation Subset:  IM    
Leonard J. Chabert Medical Center and Louisiana State University Health Sciences Center, Houma, LA 70363, USA.
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MeSH Terms
Anemia / complications*,  economics
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Disease Management
Heart Failure / complications,  economics,  mortality*
Middle Aged
Proportional Hazards Models
Prospective Studies
Receptors, Angiotensin / antagonists & inhibitors
Risk Assessment
Risk Factors
Socioeconomic Factors
Grant Support
HS11834-04/HS/AHRQ HHS
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Receptors, Angiotensin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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