Document Detail


The effect of amyl nitrite on the mitral valve echocardiogram in presumably healthy young adults.
MedLine Citation:
PMID:  6121685     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We analyzed the use of amyl nitrite as a provocative factor in the diagnosis of mitral valve prolapse in a population of healthy young adults. Sixty-five men and 11 women underwent continuous M-mode echocardiographic and phonocardiographic monitoring before, during and after the administration of inhaled amyl nitrite. All of the 76 subjects had normal baseline echocardiograms, and all had a satisfactory hemodynamic response to amyl nitrite. Mitral valve prolapse, defined by echocardiography and phonocardiography, was not provoked in any of the subjects. Therefore, we concluded that, although this technique may be difficult, significant false-positive results should not occur if adherence to strict diagnostic criteria takes place.
Authors:
A P Morise; T C Gibson; S M Davis; B J Bonazinga; J A Sbarbaro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  81     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1982 Apr 
Date Detail:
Created Date:  1982-06-24     Completed Date:  1982-06-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  483-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amyl Nitrite / diagnostic use*
Echocardiography*
False Positive Reactions
Female
Heart Auscultation*
Heart Rate / drug effects*
Heart Sounds*
Humans
Male
Mitral Valve Prolapse / diagnosis*
Phonocardiography
Chemical
Reg. No./Substance:
8017-89-8/Amyl Nitrite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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