Document Detail


The effect of amino-substitution on the beta-adrenoceptor activity of 4-bromophenylethanolamines.
MedLine Citation:
PMID:  6250504     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A series of 4-bromophenylethanolamines with a variety of amino substituents has been prepared. A detailed pharmacological evaluation has been made of their beta-adrenergic activity to study how the amino substituent may effect the mixed agonist and antagonist action of a phenylethanolamine series.
Authors:
L G Letts; D M Temple; A J Orr; L R Williams
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Archives internationales de pharmacodynamie et de thérapie     Volume:  245     ISSN:  0003-9780     ISO Abbreviation:  Arch Int Pharmacodyn Ther     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-10-27     Completed Date:  1980-10-27     Revised Date:  2012-01-12    
Medline Journal Info:
Nlm Unique ID:  0405353     Medline TA:  Arch Int Pharmacodyn Ther     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  48-55     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chemical Phenomena
Chemistry
Guinea Pigs
Muscle Contraction / drug effects
Muscle, Smooth / drug effects
Phenethylamines / pharmacology*
Receptors, Adrenergic / drug effects*
Receptors, Adrenergic, beta / drug effects*
Structure-Activity Relationship
Trachea / drug effects
Chemical
Reg. No./Substance:
0/Phenethylamines; 0/Receptors, Adrenergic; 0/Receptors, Adrenergic, beta

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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