Document Detail

The effect of aging and acute illness on delayed hypersensitivity.
MedLine Citation:
PMID:  235584     Owner:  NLM     Status:  MEDLINE    
A group of standard antigens (monilia, mosquito, mumps, purified protein derivative [PPD], staphylococcus toxoid, streptokinase-streptodornase [sk-sd] and trichophyton) were applied to 321 normal volunteers, 60 patients admitted to a medical ward, and 41 patients in an intensive care unit (ICU) to evaluate their delayed hypersensitivity skin test response. Eighty-eight per cent of the normal subjects reacted with at least 5 mm. induration to one or more skin tests without any decrease in reactivity occurring with increasing age. In the hospitalized group, only 62 per cent of the ward and 63 per cent of the ICU patients reacted to the same skin tests. All (8/8) anergic ICU patients tested after discharge regained normal reactivity. Acute illness but not increasing age will impair the delayed hypersensitivity skin test response.
J Grossman; J Baum; J Gluckman; J Fusner; J J Condemi
Related Documents :
2354724 - A multivariate analysis of determinants of wound healing in patients after amputation f...
1955634 - Precision of skin prick and puncture tests with nine methods.
18404684 - Skin reactions to human papillomavirus (hpv) 16 specific antigens intradermally injecte...
15927814 - A novel method to control the balance of skin microflora part 2. a study to assess the ...
1198324 - Cholinomimetic teratogens: studies with chicken embryos.
25311694 - Diagnostic testing for hemorrhagic fevers in pakistan: 2007-2013.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of allergy and clinical immunology     Volume:  55     ISSN:  0091-6749     ISO Abbreviation:  J. Allergy Clin. Immunol.     Publication Date:  1975 Apr 
Date Detail:
Created Date:  1975-07-02     Completed Date:  1975-07-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1275002     Medline TA:  J Allergy Clin Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  268-75     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acute Disease*
Antigens, Fungal
Antigens, Viral
Culicidae / immunology
Hypersensitivity, Delayed / immunology*
Lectins / pharmacology
Lymphocyte Activation
Middle Aged
Mitosporic Fungi / immunology
Mumps virus / immunology
Myocardial Infarction / immunology
Pulmonary Embolism / immunology
Skin Tests
Staphylococcal Toxoid
Streptodornase and Streptokinase / immunology
Trichophyton / immunology
Reg. No./Substance:
0/Antigens; 0/Antigens, Fungal; 0/Antigens, Viral; 0/Lectins; 0/Staphylococcal Toxoid; 0/Tuberculin; EC 3.-/Streptodornase and Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Preparation and properties of beta-casein from buffalo's milk.
Next Document:  Inactivation of slow reacting substance of anaphylaxis by human eosinophil arylsulfatase.