Document Detail


The effect of age and spontaneous exercise on the biomechanical and biochemical properties of chicken superficial digital flexor tendon.
MedLine Citation:
PMID:  20175711     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to evaluate if spontaneous (nonforced active) exercise and age (maturation process) alter the biomechanical and biochemical properties of superficial digital flexor tendon. Chickens aged 1, 5, and 8 months were divided into two groups: caged and penned. The caged group was reared in an area of 0.5 m(2) (3 animals/cage), while the penned group was reared in an area of 60 m(2) (3 animals/area). For biochemical analysis, the tendon was divided into tensile and compressive regions for quantification of hydroxyproline and glycosaminoglycan content. Biomechanical properties were analyzed from tensile tests of intact tendons. The biomechanical measurements were taken at maximum load and maximum stress. In both the caged and penned groups, maximum load and energy absorption increased with maturation; however, the elastic modulus, maximum stress, and maximum strain did not increase with maturation. Exercise resulted in a higher load, stress, and elastic modulus in the fifth month. Collagen content increased with age in the penned group and with exercise in the fifth and eighth months. Exercise results in a higher expression of glycosaminoglycans in young tendons compared to mature tendons. Thus, low-intensity mechanical stimuli promote the synthesis and possible rearrangement of molecules in immature tendons, whereas inactivity leads to deleterious effects on the material properties (maximum stress and elastic modulus) during growth and maturation.
Authors:
Wilson Romero Nakagaki; Edson Rosa Pimentel; Gustavo Pereira Benevides; Laurecir Gomes
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Connective tissue research     Volume:  51     ISSN:  1607-8438     ISO Abbreviation:  Connect. Tissue Res.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-05     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365263     Medline TA:  Connect Tissue Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  265-73     Citation Subset:  IM    
Affiliation:
Department of Anatomy, Cell Biology, Physiology and Biophysics, Institute of Biology, State University of Campinas, Campinas, SP, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Aging / physiology*
Analysis of Variance
Animals
Biomechanics
Chickens / physiology*
Forelimb
Glycosaminoglycans / metabolism
Hydroxyproline / metabolism
Physical Conditioning, Animal*
Tendons / anatomy & histology,  physiology*
Toes / physiology*
Chemical
Reg. No./Substance:
0/Glycosaminoglycans; 51-35-4/Hydroxyproline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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