| The effect of age on prevalence of secondary forms of hypertension in 4429 consecutively referred patients. | |
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MedLine Citation:
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PMID: 7930562 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To investigate the importance of age and other variables on the prevalence of secondary forms of hypertension in a hypertension referral center. DESIGN: Over the past 18 years 4429 patients have been referred by their physicians for a 1-day blood pressure study to investigate secondary causes of hypertension. METHODS: The 1-day blood pressure study included a history and physical examination by a physician, and measurements of serum sodium, potassium, creatinine, thyroxine, thyroid stimulating hormone, stimulated plasma renin activity, blood pressure response to the angiotensin II analogue saralasin, recumbent and upright plasma catecholamines, and plasma cortisol and aldosterone after infusion of 2 liters 0.9% saline over 3-4 h. RESULTS: The prevalence of secondary forms of hypertension was 10.2%, including renovascular hypertension (3.1%), primary aldosteronism (1.4%), Cushing's syndrome (0.5%), pheochromocytoma (0.3%), primary hypothyroidism (3.0%) and a serum creatinine > 2.0 mg/dl (1.8%). There was a very significantly increased prevalence with age of secondary forms of hypertension associated with renovascular hypertension, primary hypothyroidism and renal insufficiency. The concomitant presence of atherosclerosis significantly increased the prevalence of renovascular hypertension (9.5%) and renal insufficiency (8.0%). CONCLUSIONS: Increasing age and coexisting atherosclerosis have significant effects on the prevalence of secondary forms of hypertension. |
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Authors:
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G H Anderson; N Blakeman; D H Streeten |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of hypertension Volume: 12 ISSN: 0263-6352 ISO Abbreviation: J. Hypertens. Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-11-22 Completed Date: 1994-11-22 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8306882 Medline TA: J Hypertens Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 609-15 Citation Subset: IM |
Affiliation:
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Department of Medicine, SUNY-HSC, Syracuse 13210. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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complications African Continental Ancestry Group Age Distribution Cushing Syndrome / complications European Continental Ancestry Group Female Humans Hyperaldosteronism / complications Hypertension / epidemiology*, ethnology, etiology* Hypothyroidism / complications Kidney Failure, Chronic / complications Male Middle Aged Pheochromocytoma / complications Prevalence Referral and Consultation |
| Grant Support | |
ID/Acronym/Agency:
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AG 03055/AG/NIA NIH HHS; HL 26748/HL/NHLBI NIH HHS; RR229/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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