Document Detail

The effect of age on the microheterogeneous pattern of human myelin basic protein.
MedLine Citation:
PMID:  6207079     Owner:  NLM     Status:  MEDLINE    
Dry weight, total basic protein and myelin basic protein (MBP) in human corpus callosum tissue were found to be significantly reduced with age, confirming other reports. The heterogeneous patterns of the MBP samples were investigated and could be classified into three groups: a normal one with peak 1 larger than peak 3; an old-age pattern with peak 1 smaller than peak 3; and a pathological pattern with peak 1 greatly reduced. Because peak 1 is the only one which is significantly reduced with age, it is suggested that future investigations could be simplified. The physiological and pathophysiological role of MBP heterogeneity is discussed.
B Riederer; C G Honegger; H J Tobler; J Ulrich
Related Documents :
16511659 - Bone regeneration using rhbmp-2 induction in hemimandibulectomy type defects of elderly...
1791899 - Relevance of the rodent model to human aging studies.
7571399 - Biochemical characterization and localization of jc virus large t antigen phosphorylati...
23860129 - Ageing of the heart reversed by youthful systemic factors!
24976619 - Association of central serotonin transporter availability and body mass index in health...
17606349 - Telomeric dna length in cerebral gray and white matter is associated with longevity in ...
8803829 - Cerebral oximetry in dead subjects.
11545229 - Ontogeny of vestibular compound action potentials in the domestic chicken.
8286999 - Structure and correlates of alcohol dependence in clinical samples in the united states...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gerontology     Volume:  30     ISSN:  0304-324X     ISO Abbreviation:  Gerontology     Publication Date:  1984  
Date Detail:
Created Date:  1984-11-01     Completed Date:  1984-11-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7601655     Medline TA:  Gerontology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  234-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Chromatography, Ion Exchange
Corpus Callosum / metabolism*,  physiology
Electrophoresis, Polyacrylamide Gel
Middle Aged
Myelin Basic Proteins / analysis,  physiology*
Myelin Proteins / analysis
Reg. No./Substance:
0/Myelin Basic Proteins; 0/Myelin Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Aging-associated pancreatic exocrine insufficiency in the unanesthetized rat.
Next Document:  Silver staining of human aqueous humor proteins resolved by gel electrophoresis.