Document Detail

The effect of age of disease onset on neuropsychological performance in Parkinson's disease.
MedLine Citation:
PMID:  3346689     Owner:  NLM     Status:  MEDLINE    
One hundred and eight noninstitutionalized patients with Parkinson's disease were studied to find out whether the age of disease onset affects patients' cognitive, memory and psychomotor performance. "Early onset" patients (whose disease began before 60 years of age) showed a wide spectrum of impairments in neuropsychological performance compared with age-matched normal subjects. However, only one (2%) of these patients was demented according to DSM III criteria. Dementia was more frequent in patients with equivalent disease duration, but with late onset of disease (over 60 years); 13 of such patients (25%) were demented. The present study supports previous findings which show that dementia increases with advancing age in Parkinson's disease. It also suggests that cognitive changes are also found in patients with early onset of disease.
M Hietanen; H Teräväinen
Related Documents :
134859 - A comparison of the dermatogram with other indices for the diagnosis of down's syndrome.
19352589 - Negative effects of anemia on quality of life and its improvement by complete correctio...
10520939 - Clinical and pathological evidence for a frontal variant of alzheimer disease.
19330339 - Tdp-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degen...
19864909 - Subcortical vascular dementia biomarker pattern in mild cognitive impairment.
20847429 - Neurovascular coupling in parkinson's disease patients: effects of dementia and acetylc...
20080919 - Clinical improvement in rheumatoid arthritis is associated with healthier microvascular...
22034779 - Cerebral microdialysis: perioperative monitoring and treatment of severe neurosurgical ...
8115199 - Evidence of a congenital midline brain anomaly in pituitary dwarfs: a magnetic resonanc...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  51     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-04-11     Completed Date:  1988-04-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  244-9     Citation Subset:  IM    
Department of Neurology, University of Helsinki, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Delirium, Dementia, Amnestic, Cognitive Disorders / psychology*
Dementia / psychology
Depressive Disorder / psychology
Middle Aged
Neuropsychological Tests*
Parkinson Disease / psychology*
Psychomotor Performance
Reaction Time
Wechsler Scales

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Postural adjustments associated with rapid voluntary arm movements. II. Biomechanical analysis.
Next Document:  A new metabolic muscle disease due to abnormal hexokinase activity.