Document Detail


The effect of age of disease onset on neuropsychological performance in Parkinson's disease.
MedLine Citation:
PMID:  3346689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred and eight noninstitutionalized patients with Parkinson's disease were studied to find out whether the age of disease onset affects patients' cognitive, memory and psychomotor performance. "Early onset" patients (whose disease began before 60 years of age) showed a wide spectrum of impairments in neuropsychological performance compared with age-matched normal subjects. However, only one (2%) of these patients was demented according to DSM III criteria. Dementia was more frequent in patients with equivalent disease duration, but with late onset of disease (over 60 years); 13 of such patients (25%) were demented. The present study supports previous findings which show that dementia increases with advancing age in Parkinson's disease. It also suggests that cognitive changes are also found in patients with early onset of disease.
Authors:
M Hietanen; H Teräväinen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  51     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-04-11     Completed Date:  1988-04-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  244-9     Citation Subset:  IM    
Affiliation:
Department of Neurology, University of Helsinki, Finland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Delirium, Dementia, Amnestic, Cognitive Disorders / psychology*
Dementia / psychology
Depressive Disorder / psychology
Female
Humans
Male
Middle Aged
Neuropsychological Tests*
Parkinson Disease / psychology*
Psychometrics
Psychomotor Performance
Reaction Time
Wechsler Scales
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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