Document Detail

The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study.
MedLine Citation:
PMID:  23161338     Owner:  NLM     Status:  Publisher    
Via influencing brain plasticity, aerobic exercise could contribute to the treatment of schizophrenia patients. As previously shown, physical exercise increases hippocampus volume and improves short-term memory. We now investigated gray matter density and brain surface expansion in this sample using MRI-based cortical pattern matching methods. Comparing schizophrenia patients to healthy controls before and after 3 months of aerobic exercise training (cycling) plus patients playing table football yielded gray matter density increases in the right frontal and occipital cortex merely in healthy controls. However, respective exercise effects might be attenuated in chronic schizophrenia, which should be verified in a larger sample.
Peter Falkai; Berend Malchow; Thomas Wobrock; Oliver Gruber; Andrea Schmitt; William G Honer; Frank-Gerald Pajonk; Frank Sun; Tyrone D Cannon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-17
Journal Detail:
Title:  European archives of psychiatry and clinical neuroscience     Volume:  -     ISSN:  1433-8491     ISO Abbreviation:  Eur Arch Psychiatry Clin Neurosci     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9103030     Medline TA:  Eur Arch Psychiatry Clin Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, Nußbaumstr 7, 80336, Munich, Germany.
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