Document Detail

The effect of admission physiological variables on 30 day outcome after stroke.
MedLine Citation:
PMID:  16257215     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Potentially modifiable physiological variables may influence stroke prognosis but their independence from modifiable factors remains unclear. METHODS: Admission physiological measures (blood pressure, heart rate, temperature and blood glucose) and other unmodifiable factors were recorded from patients presenting within 48 hours of stroke. These variables were compared with the outcomes of death and death or dependency at 30 days in multivariate statistical models. RESULTS: In the 186 patients included in the study, age, atrial fibrillation and the National Institutes of Health Stroke Score were identified as unmodifiable factors independently associated with death and death or dependency. After adjusting for these factors, none of the physiological variables were independently associated with death, while only diastolic blood pressure (DBP) > or = 90 mmHg was associated with death or dependency at 30 days (p = 0.02). CONCLUSIONS: Except for elevated DBP, we found no independent associations between admission physiology and outcome at 30 days in an unselected stroke cohort. Future studies should look for associations in subgroups, or by analysing serial changes in physiology during the early post-stroke period.
Andrew A Wong; James P Davis; Philip J Schluter; Robert D Henderson; John D O'Sullivan; Stephen J Read
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-10-27
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  12     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-12-05     Completed Date:  2006-05-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  905-10     Citation Subset:  IM    
Department of Neurology, Royal Brisbane and Women's Hospital, Herston, University of Queensland, St. Lucia, Queensland, Australia.
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MeSH Terms
Aged, 80 and over
Blood Glucose / physiology
Blood Pressure / physiology
Body Temperature / physiology
Diagnostic Tests, Routine*
Heart Rate / physiology
Middle Aged
Patient Admission
Predictive Value of Tests
Risk Factors
Stroke / physiopathology*
Treatment Outcome
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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