| The effect of acebutolol on cardiac arrhythmias in patients with chronic coronary artery disease. | |
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MedLine Citation:
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PMID: 6102434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of the beta-blocking drug acebutolol on the severity of cardiac arrhythmias and the incidence of exercise-induced arrhythmias was studied in 15 patients with chronic coronary artery disease using ambulatory Holter monitoring and bicycle ergometry. We found a significantly lower grading of arrhythmias both on long-term ECGs and during and after exercise. Furthermore, there was a significant decrease in the incidence of VPBs during and after exercise (18.15 +/- 7.7 on placebo vs. 3.46 +/- 1.7 on acebutolol). It is concluded that acebutolol favorably influences the incidence and severity of ventricular arrhythmias in patients with chronic coronary artery disease. |
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Authors:
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D Burckhardt; E A Raeder |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American heart journal Volume: 99 ISSN: 0002-8703 ISO Abbreviation: Am. Heart J. Publication Date: 1980 Apr |
Date Detail:
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Created Date: 1980-05-23 Completed Date: 1980-05-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 443-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acebutolol
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therapeutic use* Adrenergic beta-Antagonists* Aged Arrhythmias, Cardiac / complications, drug therapy* Coronary Disease / complications* Electrocardiography Exercise Test Female Heart Rate / drug effects Heart Ventricles / physiopathology Humans Male Middle Aged Placebos |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Placebos; 37517-30-9/Acebutolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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