Document Detail

The effect of TMS on visual motion sensitivity: an increase in neural noise or a decrease in signal strength?
MedLine Citation:
PMID:  21543749     Owner:  NLM     Status:  Publisher    
The underlying mechanisms of action of transcranial magnetic stimulation (TMS) are still a matter of debate. TMS may impair a subject's performance by increasing neural noise, by suppressing the neural signal, or both. Here we delivered a single pulse of TMS (spTMS) to V5/MT during a motion direction discrimination task while concurrently manipulating the level of noise in the motion stimulus. Our results indicate that spTMS essentially acts by suppressing the strength of the relevant visual signal. We suggest that TMS may induce a pattern of neural activity that complements the ongoing activation elicited by the sensory signal in a manner that partially impoverishes that signal.
Manuela Ruzzoli; Arman Abrahamyan; Colin W G Clifford; Carlo Alberto Marzi; Carlo Miniussi; Justin A Harris
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-4
Journal Detail:
Title:  Journal of neurophysiology     Volume:  -     ISSN:  1522-1598     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375404     Medline TA:  J Neurophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1University of Verona.
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