Document Detail

The effect of PMSG dose on the incidence of chromosomal anomalies in mouse embryos fertilized in vitro.
MedLine Citation:
PMID:  881666     Owner:  NLM     Status:  MEDLINE    
Chromosomal analysis of first-cleavage mouse embryos obtained by fertilization of TO eggs with TO spermatozoa in vitro revealed that the incidence of polyploidy was proportional to the dose of PMSG given to the donor females. The dose-response was shown to be linear, with the level of polyploidy rising from 8-0% with a PMSG dose of 1-5 i.u./female to 20-8% with 10-0 i.u./female. A total of 64 polyploid embryos was found among the 452 examined and in all cases the polyploidy was the result of polyspermy or fertilization by diploid spermatozoa.
I Maudlin; L R Fraser
Related Documents :
3767816 - Effect of medicated feed on tracheal infection and population of mycoplasma galliseptic...
2282066 - An avian model for the study of acute hemolytic anemia in the domestic fowl (gallus dom...
20872696 - Evaluation of the impact of in-ovo exposure to dicofol on avian reproduction.
25492586 - Sublethal and hormesis effects of imidacloprid on the soybean aphid aphis glycines.
9021816 - Engraftment failure following bone marrow transplantation in children with thalassemia ...
4533696 - Intraamniotic administration of prostaglandin f2alpha for therapeutic abortion.
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  50     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-09-17     Completed Date:  1977-09-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  275-80     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dose-Response Relationship, Drug
Fertilization* / drug effects
Gonadotropins, Equine / administration & dosage,  pharmacology*
Reg. No./Substance:
0/Gonadotropins, Equine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Developmental effects of the uterine environment: dependence on fetal sex in rats.
Next Document:  Qualitative and quantitative examination of the proteins of rat uterine luminal fluid during pro-oes...