| The effect of Oligonol intake on cortisol and related cytokines in healthy young men. | |
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MedLine Citation:
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PMID: 20607065 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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This study investigated the effects of Oligonol intake on cortisol, interleukin (IL)-1beta, and IL-6 concentrations in the serum at rest and after physical exercise loading. Nineteen healthy sedentary male volunteers participated in this study. The physical characteristics of the subjects were: a mean height of 174.2 +/- 2.7 cm, a mean weight of 74.8 +/- 3.6 kg and a mean age of 22.8 +/- 1.3 years. Each subject received 0.5 L water with Oligonol (100 mg/day) (n = 10) or a placebo (n = 9) daily for four weeks. The body composition, the white blood cell (WBC) and differential counts as well as the serum cortisol, IL-1beta, and IL-6 concentrations were measured before and after Oligonol intake. The cortisol concentration and serum levels of IL-1beta and IL-6 after Oligonol intake were significantly decreased compared to before treatment (P < 0.01, respectively). In addition, the rate of increase of these factors after exercise was decreased compared to the placebo group. There was no change in the WBC and differential cell counts. These results suggest that oral Oligonol intake for four weeks had a significant effect on inhibition of inflammatory markers in healthy young men. |
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Authors:
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Jeong-Beom Lee; Young-Oh Shin; Young-Ki Min; Hun-Mo Yang |
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Publication Detail:
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Type: Journal Article Date: 2010-06-29 |
Journal Detail:
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Title: Nutrition research and practice Volume: 4 ISSN: 2005-6168 ISO Abbreviation: Nutr Res Pract Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101311052 Medline TA: Nutr Res Pract Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 203-7 Citation Subset: - |
Affiliation:
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Department of Physiology, College of Medicine, Soonchunhyang University, 366-1 Ssang yong-dong, Cheonan 331-946, Korea. |
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