Document Detail

The effect of NitrAdine on the Candida levels of maxillary removable appliances.
MedLine Citation:
PMID:  22299124     Owner:  NLM     Status:  In-Data-Review    
Objective: Candida colonization is a consequence of orthodontic treatment and can lead to oral candidosis as a complication of maxillary removable appliance treatment. During orthodontic treatment, it is important to minimize colonization to prevent active infection that could consequently interfere with treatment. Hygiene is the most important factor in managing colonization; in this study, the efficacy of NitrAdine to reduce Candida was tested. Method and Materials: A randomized, double-blind, placebo-controlled trial was performed. Ninety-two patients 11 to 14 years of age were recruited at the Children's and the University Dental Clinics at Mater Dei Hospital, Tal-Qroqq, Msida, Malta. Forty-four patients used the product with NitrAdine, while 48 patients used a placebo. Sampling employing the imprint technique was performed before and after the product was used. Brilliance Candida agar was used for cultures and identification. Further identification was performed using Auxacolor 2 when required. Results: The control group had a statistically significant increase in Candida during treatment, while the experimental group had a nonstatistically significant decrease. Conclusion: It was concluded that NitrAdine may reduce the Candida burden in maxillary removable appliances. Larger sample sizes are needed to achieve statistical significance. Quintessence Int 2012;43:239-245.
Stephen Decelis; Simon Camilleri; Ethel Vento Zahra; Erica Scerri; Bart De Wever
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Quintessence international (Berlin, Germany : 1985)     Volume:  43     ISSN:  1936-7163     ISO Abbreviation:  Quintessence Int     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342677     Medline TA:  Quintessence Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  239-45     Citation Subset:  D    
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