Document Detail


The effect of NSAID on T-cell ratios in marginal periodontitis.
MedLine Citation:
PMID:  9497636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The use of NSAID in the treatment of periodontal disease can augment the conventional periodontal therapy. NSAID can block prostaglandin synthesis which is responsible for the progression of periodontal disease. Inhibition of prostaglandin synthesis reduces the alveolar bone loss, loss of attachment, gingival inflammation and consequently pocket depth. Results of the present study show that the use of NSAID increases the T-cell ratios indicating an improvement of T-cell function which is represented clinically by the reduction in G.I scores.
Authors:
M el-Sherbiny; M A Shoeib; O A Daahab
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Egyptian dental journal     Volume:  41     ISSN:  0070-9484     ISO Abbreviation:  Egypt Dent J     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1998-04-16     Completed Date:  1998-04-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0373212     Medline TA:  Egypt Dent J     Country:  EGYPT    
Other Details:
Languages:  eng     Pagination:  1025-30     Citation Subset:  D; X    
Affiliation:
Department of Oral Medicine and Periodontology, Cairo University.
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MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / pharmacology,  therapeutic use*
Biopsy
CD4-CD8 Ratio / drug effects*
Gingiva / pathology
Humans
Ibuprofen / pharmacology,  therapeutic use*
Periodontal Index
Periodontitis / diagnosis,  drug therapy*,  immunology*
Time Factors
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 15687-27-1/Ibuprofen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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