| The effect of LongoVital on recurrent aphthous stomatitis in a controlled clinical trial. | |
| | |
MedLine Citation:
|
PMID: 15921331 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: The aim of this study was to evaluate the effect of daily intake of LongoVital (LV) (herbal vitamin tablets) in the prevention of RAS. MATERIALS AND METHODS: A group of 78 consecutively referred patients was enrolled to a three-months pretreatment period. Fifty subjects were then randomly allocated to an LV-group (n = 25) or a placebo group (N = 25). A double blind, stratified-randomised clinical case-control study was performed during six months. Number and size of the ulcers were registered by the patients using a standardized chart. The degree of discomfort was recorded on a 100 mm horizontal visual analogue scale (VAS-scale). RESULTS: The three-months pretreatment period revealed that the most dominant symptoms were pain (78%) followed by burning sensation (18%). No significant differences between the two groups were found during this period when a comparison was made at the end of the study. After the intervention period the number of aphthous ulcers/month decreased significantly in the LV-group (p = 0.02). The number of days in pain/month were also reduced (p < 0.001). If a 50% reduction of number of aphthous ulcers and days in pain were considered as clinically relevant, no statistical significant differences were found between the groups. CONCLUSION: Thus, no strong evidence was found that justified a recommendation of LV as a general drug for treatment of RAS. |
| | |
Authors:
|
John Bratel; Magnus Hakeberg; Mats Jontell |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Oral health & preventive dentistry Volume: 3 ISSN: 1602-1622 ISO Abbreviation: Oral Health Prev Dent Publication Date: 2005 |
Date Detail:
|
Created Date: 2005-05-30 Completed Date: 2005-06-14 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 101167768 Medline TA: Oral Health Prev Dent Country: England |
Other Details:
|
Languages: eng Pagination: 3-8 Citation Subset: D; IM |
Affiliation:
|
Clinic of Oral medicine, Odontologen, Public Dental Service, Göteborg, Sweden. john.bratel@vgregion.se |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Double-Blind Method Drug Combinations Female Humans Male Middle Aged Phytotherapy* Plant Preparations / therapeutic use* Plant Structures Plants, Medicinal Recurrence / prevention & control Statistics, Nonparametric Stomatitis, Aphthous / prevention & control* Tablets Vitamins / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Drug Combinations; 0/Plant Preparations; 0/Tablets; 0/Vitamins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Advances in tracheal prostheses
Next Document: Causes and prevention of dental caries: a perspective on cases and incidence.