Document Detail


The effect of Helicobacter pylori infection on gastric emptying of digestible and indigestible solids in patients with nonulcer dyspepsia.
MedLine Citation:
PMID:  8633494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: There is no general agreement with regard to the effect of Helicobacter pylori infection on gastric emptying in patients with nonulcer dyspepsia. METHODS: We performed the 14C urea breath test as well as simultaneous recordings of scintigraphic gastic emptying and gastric clearance of radiopaque markers to determine the effect of Helicobacter pylori infection on gastric emptying of digestible and indigestible solids in nonulcer dyspepsia patients. RESULTS: Sixty patients, 30 males and 30 females, were enrolled in the study. There were 22 patients (36.7%) without and 38 patients (63.3%) with H. pylori infection. Twenty-four of the 60 patients (40%) showed normal and 36 patients (60%) showed delayed gastric emptying of digestible solids. In addition, 21 patients (35%) showed normal and 39 patients (63%) showed delayed gastric emptying of indigestible solids. There was no correlation between delayed gastric emptying of digestible and indigestible solids (p > 0.05, difference not significant). Although not statistically significant, the incidence of delayed indigestible solid emptying was higher than that of delayed digestible solid emptying (65% vs. 60%). Among different patterns of gastric emptying, no difference was noted between the patients with and without H. pylori infection. CONCLUSION: Delayed gastric emptying of indigestible solids is as common as delayed gastric emptying of digestible solids in nonulcer dyspepsia patients. The status of H. Pylori infection appeared not to influence the incidence of delayed gastric emptying of digestible and indigestible solids.
Authors:
C S Chang; G H Chen; C H Kao; S J Wang; S N Peng; C K Huang
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  91     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1996 Mar 
Date Detail:
Created Date:  1996-07-01     Completed Date:  1996-07-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  474-9     Citation Subset:  IM    
Affiliation:
Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Breath Tests
Carbon Radioisotopes / diagnostic use
Chi-Square Distribution
Digestion / physiology*
Dyspepsia / physiopathology*,  radionuclide imaging
Female
Gastric Emptying*
Helicobacter Infections / microbiology*,  physiopathology,  radionuclide imaging
Helicobacter pylori*
Humans
Male
Middle Aged
Organotechnetium Compounds / diagnostic use
Phytic Acid / diagnostic use
Urea / analysis
Chemical
Reg. No./Substance:
0/Carbon Radioisotopes; 0/Organotechnetium Compounds; 0/technetium phytate; 57-13-6/Urea; 83-86-3/Phytic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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