Document Detail


The effect of 3-methylhistidine in food on its urinary excretion in man.
MedLine Citation:
PMID:  7438717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. To establish whether 3-methylhistidine in food is quantitatively excreted in the urine, five normal adults on a vegetarian diet were given known amounts of 3-methylhistidine in meat or fish. The mean cumulative 5-day increment in 3-methylhistidine excretion in non-hydrolysed urine accounted for an average of 90% of the 3-methylhistidine given during the first 3 days of this period. 2. To define the variation in urinary 3-methylhistidine on a constant mixed intake, the daily 3-methylhistidine excretion was measured for 6 days in four patients on a metabolic "balance" diet. The mean daily variation was less than 10%. 3. The results show that under the conditions of this study the increase in urinary 3-methylhistidine above basal levels can be quantitatively accounted for by the 3-methylhistidine content of additional food; in subjects on a constant diet it should be possible to detect relatively small changes in 3-methylhistidine excretion.
Authors:
M Elia; A Carter; S Bacon; R Smith
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical science (London, England : 1979)     Volume:  59     ISSN:  0143-5221     ISO Abbreviation:  Clin. Sci.     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-02-26     Completed Date:  1981-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905731     Medline TA:  Clin Sci (Lond)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  509-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Diet*
Diet, Vegetarian
Female
Histidine / analogs & derivatives*
Humans
Male
Meat / analysis
Methylhistidines / analysis,  urine*
Chemical
Reg. No./Substance:
0/Methylhistidines; 71-00-1/Histidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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