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The effect of 2 different distraction-compression models on new bone generation.
MedLine Citation:
PMID:  22907114     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: To compare the stimulating effect of distraction and 2 different distraction-compression models on maturation of new bone during healing.
MATERIALS AND METHODS: Thirty adult Sprague-Dawley rats underwent unilateral mandibular osteotomy. The animals were divided into 3 groups. A unidirectional external distraction device was fixed to the mandible. A total of 4 mm of distraction was planned in all groups. After a latency period of 3 days, 0.2 mm of distraction was performed twice a day for 10 days in the distraction group. In the intermittent distraction-compression group, 0.2 mm of distraction was performed twice a day for 3 days, followed by 0.2 mm of compression twice a day for 1 day. In the overdistraction-compression group, 0.2 mm of distraction was performed twice a day for 14 days, followed by 0.2 mm of compression twice a day for 4 days. After a consolidation period of 6 weeks in all groups, animals were killed for macroscopic, microscopic, and radiologic evaluation.
RESULTS: Radiologic evaluation proved that more mature bone generation occurred in the groups in which compression was added to distraction. The number of osteoblasts in the intermittent distraction-compression group was significantly higher than that in the distraction group and overdistraction-compression group (P < .001). The highest number of vessels was found in the intermittent distraction-compression group (17.7 ± 6.4) (P < .001).
CONCLUSIONS: The intermittent distraction-compression model was found to generate greater new bone compared with distraction alone. In clinical applications, to increase the quality of the bone and to shorten the consolidation period, compression can be applied during distraction.
Authors:
Sevin Ozgül; Zeynep D Akdeniz; Ozhan Celebiler; Toros Alcan; Aydın Sav
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  70     ISSN:  1531-5053     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e490-9     Citation Subset:  AIM; D; IM    
Copyright Information:
Copyright © 2012 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
Affiliation:
Specialist, Department of Plastic, Reconstructive and Aesthetic Surgery, School of Medicine, Marmara University, Istanbul, Turkey.
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