Document Detail


The effect of 1.5% timolol maleate on intraocular pressure.
MedLine Citation:
PMID:  345735     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A controlled trial was instituted to compare the effect on intraocular pressure of topical administration of timolol maleate with epinephrine hydrochloride. A bottling error by the manufacturer resulted in the placebo bottles containing 1.5% timolol maleate. This drug given twice a day for two weeks significantly reduced intraocular pressure and produced no side effects.
Authors:
R Ritch; N A Hargett; S M Podos
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  56     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  6-10     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Clinical Trials as Topic
Depression, Chemical
Double-Blind Method
Epinephrine / administration & dosage,  pharmacology
Humans
Intraocular Pressure / drug effects*
Placebos
Propanolamines / pharmacology*
Technology, Pharmaceutical
Timolol / administration & dosage,  pharmacology*
Chemical
Reg. No./Substance:
0/Placebos; 0/Propanolamines; 26839-75-8/Timolol; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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