Document Detail

The early steps of neural crest development.
MedLine Citation:
PMID:  11429279     Owner:  NLM     Status:  MEDLINE    
The neural crest is an intriguing cell population that gives rise to many derivatives which are all generated far from their final destinations. From its induction to the delamination of the cells, multiple signalling pathways converge to regulate the expression of effector genes, the products of which endow the cells with invasive and migratory properties reminiscent of those displayed by malignant cells in tumours. As such, the neural crest constitutes an excellent model to study cell migration.
M A Nieto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Mechanisms of development     Volume:  105     ISSN:  0925-4773     ISO Abbreviation:  Mech. Dev.     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-06-28     Completed Date:  2001-12-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9101218     Medline TA:  Mech Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  27-35     Citation Subset:  IM    
Instituto Cajal, CSIC, Doctor Arce, 37, 28002, Madrid, Spain.
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MeSH Terms
Bone Morphogenetic Proteins / physiology
Cadherins / physiology
Cell Adhesion
Cell Movement
Epithelial Cells / metabolism
Mesoderm / metabolism
Models, Biological
Neural Crest / embryology*,  physiology*
Signal Transduction
Reg. No./Substance:
0/Bone Morphogenetic Proteins; 0/Cadherins

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