Document Detail

The early-infantile epileptic encephalopathy with suppression-burst: developmental aspects.
MedLine Citation:
PMID:  3434712     Owner:  NLM     Status:  MEDLINE    
A clinico-electroencephalographic study on 14 cases of the early-infantile epileptic encephalopathy with suppression-burst (EIEE) including long-term follow-up studies for one year 8 months to 12 years 2 months disclosed the specificity of EIEE in its developmental aspects. With age, clinical evolution from EIEE to the West syndrome was observed in as many as 10 cases, among which two cases showed further transition to the Lennox-Gastaut syndrome. Electroencephalographically, suppression-burst pattern gradually began to disappear from age of 3 months and disappeared by 6 months in all the cases, transforming to hypsarhythmia in 10 cases from 2 to 6 months of age, showing further transition to diffuse slow spike-and-waves in 2 cases at one year and one month and at 3 years and one month of age, respectively. Changing pattern of EEG were classifiable into two types which strongly related to the prognosis. These findings indicated EIEE to be an independent epileptic syndrome as the earliest form of the age-dependent epileptic encephalopathy.
S Ohtahara; Y Ohtsuka; Y Yamatogi; E Oka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain & development     Volume:  9     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  1987  
Date Detail:
Created Date:  1988-03-15     Completed Date:  1988-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  371-6     Citation Subset:  IM    
Department of Developmental Neuroscience and Child Neurology, Okayama University Medical School, Japan.
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MeSH Terms
Epilepsy / etiology,  physiopathology*
Follow-Up Studies
Infant, Newborn
Spasms, Infantile / physiopathology

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