Document Detail

The early evolution of the tetrapod humerus.
MedLine Citation:
PMID:  15064415     Owner:  NLM     Status:  MEDLINE    
A tetrapod humerus from the Late Devonian of Pennsylvania has a novel mix of primitive and derived characters. A comparative analysis of this fossil and other relevant humeri from the Devonian shows that the role of the limb in propping the body arose first in fish fins, not tetrapod limbs. The functional diversity of the earliest known limbs includes several different kinds of appendage design. This functional diversity was achieved with a humeral architecture that was remarkably conserved during the Devonian.
Neil H Shubin; Edward B Daeschler; Michael I Coates
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  304     ISSN:  1095-9203     ISO Abbreviation:  Science     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-05     Completed Date:  2004-04-14     Revised Date:  2007-03-19    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  United States    
Other Details:
Languages:  eng     Pagination:  90-3     Citation Subset:  IM    
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA.
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MeSH Terms
Extremities / anatomy & histology*
Fishes / anatomy & histology,  physiology
Humerus / anatomy & histology*
Vertebrates / anatomy & histology*,  physiology
Comment In:
Science. 2004 Apr 2;304(5667):57-8   [PMID:  15060312 ]
Science. 2004 Sep 17;305(5691):1715; author reply 1715   [PMID:  15375249 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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