Document Detail

Is early anticoagulation necessary after biological aortic valve replacement?
MedLine Citation:
PMID:  18068239     Owner:  NLM     Status:  MEDLINE    
Early antithrombotic therapy after biological aortic valve replacement (AVR) is controversial. The aim of this study was to determine the rate of thromboembolic events (TE) without anticoagulation treatment during the first 3 months after surgery. Out of 143 consecutive patients who underwent biological AVR from January 1998 to December 2004, 127 patients who did not receive anticoagulation were included (89%). Events during the first 3 months after surgery included: 2 strokes (1.5%), 2 major bleedings (1.5%) and 9 deaths (7%) (none of them due to TE). In conclusion, the management of patients without antithrombotic treatment after biological AVR seems to be safe due to a low rate of TE.
Mariano Noel Benzadón; Jorge Mario Thierer; Marcelo Trivi; Mariano Vrancic; Sebastian Fieg; Fernando Piccinini; Guillermo Vaccarino; Daniel Navia
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Publication Detail:
Type:  Comparative Study; Letter     Date:  2007-12-18
Journal Detail:
Title:  International journal of cardiology     Volume:  128     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-04     Completed Date:  2009-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  422-3     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Anticoagulants / therapeutic use*
Aortic Valve / drug effects,  pathology,  surgery*
Follow-Up Studies
Heart Valve Prosthesis / adverse effects
Heart Valve Prosthesis Implantation / adverse effects*
Middle Aged
Postoperative Complications / epidemiology,  prevention & control
Retrospective Studies
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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