| A dysbalanced immune system in cryptogenic Lennox-Gastaut syndrome. | |
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MedLine Citation:
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PMID: 7863268 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In children with cryptogenic Lennox-Gastaut syndrome we found a functionally impaired humoral immune response to a primary antigen (haemocyanin), despite signs of a triggered immune system consisting of elevated IgG concentrations. This combination of immunological findings, considered to be the expression of a dysbalanced-triggered as well as functionally impaired-immune system, has also been described in an auto-immune disease like systemic lupus erythaematodes in humans, and in genetically epilepsy-prone rats. The interactions between the immune system and the nervous system in Lennox-Gastaut syndrome will be discussed. |
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Authors:
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B G van Engelen; C M Weemaes; W O Renier; J A Bakkeren; G F Borm; P F Strengers |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Scandinavian journal of immunology Volume: 41 ISSN: 0300-9475 ISO Abbreviation: Scand. J. Immunol. Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-03-17 Completed Date: 1995-03-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0323767 Medline TA: Scand J Immunol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 209-13 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, University Hospital, Nijmegen, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Child, Preschool Epilepsy, Absence / immunology* Female Hemocyanin / immunology Humans Immunoglobulin A / blood Immunoglobulin G / blood Immunoglobulin Isotypes / blood* Immunoglobulin M / blood Infant Male Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin Isotypes; 0/Immunoglobulin M; 9013-72-3/Hemocyanin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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