Document Detail


The dynamic and static elastic response of the abdominal aorta of the dog.
MedLine Citation:
PMID:  1201576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The dynamic and static elastic response of the abdominal aorta was studied in beagle dogs of similar age and weight. The dynamic response was measured in situ by means of an optical transmission wedge resting on the exposed vessel to record the pulsatile changes in wall displacement and the pressure pulse recorded at the same site via a hypodermic needle. The static response was recorded (1) in situ by observing the change in radius which occurred with a change in the mean blood pressure, (2) post mortem using both transmission wedge and radiographic techniques. The change in radius (deltaR) for a change in pressure (deltaP=20 mm Hg[2.67kPa]) was calculated for both the dynamic and static cases. It was found that the aorta was stiffer for the dynamic case, the extent of the stiffening being dependent on the mean pressure. At pressures less than 80 mm Hg (10.64 kPa) the dynamic/static deltaR ratio was 1.8 decreasing to 1.1 at 160 mm Hg (21.28 kPa). This behaviour is interpreted in terms of smooth muscle relaxation and the subsequent transference of circumferential tension to collagen.
Authors:
D L Newman; N L Bowden; R G Gosling
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular research     Volume:  9     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1975 Sep 
Date Detail:
Created Date:  1976-03-01     Completed Date:  1976-03-01     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  679-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta, Abdominal / physiology*
Blood Pressure
Collagen / physiology
Dogs
Elasticity
Muscle, Smooth / physiology
Pressure
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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