Document Detail

The durability of laparoscopic Nissen fundoplication: 11-year outcomes.
MedLine Citation:
PMID:  17562117     Owner:  NLM     Status:  MEDLINE    
Laparoscopic Nissen fundoplication (LNF) has become the most commonly performed antireflux procedure since its introduction in 1991. There are few studies with greater than 5-year outcomes. Herein we report a series of 312 consecutive patients who underwent primary LNF before 1996. Follow-up of more than 6 years was available in 166 patients, and the mean follow-up was 11 years (median 11.1 years, range 6.1-13.3 years). Prospective data collection included preoperative and current symptom scores (scale 0 = none to 3 = severe), as well as the level of patient satisfaction and use of antireflux medications. Total symptom score for each patient was summed from seven symptoms for a maximum value of 21. Heartburn and regurgitation were the most improved symptoms; however, all symptoms were significantly improved (P < 0.01). The total symptom score at follow-up was 2.6 down from 7.5 at baseline, with a mean difference of -4.9 (range -12 to 3). The percentage of patients stating they would have the procedure again was 93.3%, and 70% were off daily antireflux medications. Outcomes at a mean of 11 years after LNF are excellent, and the majority of patients had their symptoms resolved or significantly improved and are satisfied with their results.
Craig B Morgenthal; Matthew D Shane; Alessandro Stival; Nana Gletsu; Graham Milam; Vickie Swafford; John G Hunter; C Daniel Smith
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract     Volume:  11     ISSN:  1091-255X     ISO Abbreviation:  J. Gastrointest. Surg.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-12     Completed Date:  2007-09-27     Revised Date:  2014-10-01    
Medline Journal Info:
Nlm Unique ID:  9706084     Medline TA:  J Gastrointest Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  693-700     Citation Subset:  IM    
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MeSH Terms
Follow-Up Studies
Fundoplication / methods*
Gastroesophageal Reflux / drug therapy,  surgery*
Middle Aged
Patient Satisfaction
Treatment Outcome
Comment In:
Chirurg. 2008 Mar;79(3):261-2   [PMID:  18305913 ]
J Gastrointest Surg. 2014 Jan;18(1):157-62; discussion 162-3   [PMID:  24234243 ]

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