Document Detail

The duplication cycle in Aspergillus nidulans.
MedLine Citation:
PMID:  9344627     Owner:  NLM     Status:  MEDLINE    
The duplication cycle encompasses the spectrum of events required for the growth and division of individual cells within a fungal hyphae. Recent advances in understanding the mechanisms which underlie nuclear division and cellular morphogenesis in the filamentous fungus Aspergillus nidulans have shown that in many respects, the duplication cycle differs significantly from the cell cycles of both budding and fission yeast. The purpose of this review is to summarize these advances and to highlight the fundamental differences between the duplication cycle and the yeast cell cycles. In addition, it is argued that the duplication cycle is controlled by cellular regulatory networks which integrate the processes of nuclear division, cellular morphogenesis, and cell growth with each other. Functional dissection of these networks should help to reveal features that are unique to the hyphal mode of growth.
S D Harris
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review    
Journal Detail:
Title:  Fungal genetics and biology : FG & B     Volume:  22     ISSN:  1087-1845     ISO Abbreviation:  Fungal Genet. Biol.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-12-12     Completed Date:  1997-12-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9607601     Medline TA:  Fungal Genet Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-12     Citation Subset:  IM    
Copyright Information:
Copyright 1997 Academic Press.
Department of Microbiology, University of Connecticut Health Center, Farmington, Connecticut, 06030-3205, USA.
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MeSH Terms
Aspergillus nidulans / growth & development*
Cell Cycle / physiology*

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