| Is double data entry necessary? The CHART trials. CHART Steering Committee. Continuous, Hyperfractionated, Accelerated Radiotherapy. | |
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MedLine Citation:
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PMID: 7851109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is some controversy over the need for double data entry in clinical trials. In particular, does the number and types of errors identified with this approach justify the extra effort involved? We report the results of a study carried out to address this question. Our main outcome measure was the frequency and types of errors involved in the entry of data for the CHART (continuous, hyperfractionated, accelerated radiotherapy) trials. Data were reentered for a sample of 44 patients by a data manager other than the one making the initial entry. The second entry was then compared with the first entry. The error rate for the two entries combined was 14 per 10,000 data items (fields) (95% confidence interval 10, 19). The error rate for the initial entry alone was 15 per 10,000 fields (95% confidence interval 9.5, 22), and the vital/important error rate (defined as any error on a principal outcome measure or a major error on any other endpoint or variable) was 2.5 per 10,000 fields (95% confidence interval 0.68, 6.4). On this evidence double data entry is not performed for the CHART trials. |
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Authors:
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D Gibson; A J Harvey; V Everett; M K Parmar |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: Controlled clinical trials Volume: 15 ISSN: 0197-2456 ISO Abbreviation: Control Clin Trials Publication Date: 1994 Dec |
Date Detail:
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Created Date: 1995-03-15 Completed Date: 1995-03-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8006242 Medline TA: Control Clin Trials Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 482-8 Citation Subset: IM |
Affiliation:
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Medical Research Council, Cancer Trials Office, Cambridge, England. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carcinoma, Non-Small-Cell Lung
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radiotherapy* Head and Neck Neoplasms / radiotherapy* Humans Lung Neoplasms / radiotherapy* Quality of Life Radiotherapy / economics |
| Comments/Corrections | |
Comment In:
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Control Clin Trials. 1995 Dec;16(6):453-5
[PMID:
8720022
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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