| A double-blind study of the influence of tranexamic acid on the central corneal thickness after cataract extraction. | |
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MedLine Citation:
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PMID: 345733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A double-blind study of the influence of systemic tranexamic acid on the central corneal thickness after cataract extraction was performed in 17 pairs of patients. Apart from the cataract, no were present. A sequential statistics was used to show that the increase in central corneal thickness after operation was significantly less in the tranexamic acid treated group than in the placebo group. There was no significant difference in intraocular pressure between the tranexamic acid and the placebo treated group. The possible influence of tranexamic acid on the thickness controlling mechanism of the cornea is discussed, and studies concerning the fibrinolytic system, the complement system and the aqueous humour amino acid treated patients are mentioned. |
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Authors:
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T Bramsen; L Corydon; N Ehlers |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Acta ophthalmologica Volume: 56 ISSN: 0001-639X ISO Abbreviation: Acta Ophthalmol (Copenh) Publication Date: 1978 Feb |
Date Detail:
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Created Date: 1978-05-17 Completed Date: 1978-05-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370347 Medline TA: Acta Ophthalmol (Copenh) Country: DENMARK |
Other Details:
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Languages: eng Pagination: 121-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cataract Extraction* Clinical Trials as Topic Cornea / anatomy & histology, drug effects* Cyclohexanecarboxylic Acids / pharmacology* Double-Blind Method Female Humans Intraocular Pressure / drug effects Male Middle Aged Placebos Tranexamic Acid / pharmacology* |
| Chemical | |
Reg. No./Substance:
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0/Cyclohexanecarboxylic Acids; 0/Placebos; 1197-18-8/Tranexamic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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