| The double balloon cannula: a means to prevent backward flow of retrograde cardioplegia to the right atrium. | |
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MedLine Citation:
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PMID: 17670571 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Retrograde cardioplegia (RC) delivery may result in suboptimal myocardial protection, due to leakage of cardioplegia to the right atrium. This study was undertaken to assess the efficacy of a double balloon cannula (DBC) occluding the coronary sinus ostium during RC. Fifteen patients were randomly assigned to receive RC via a conventional cannula or via the DBC. Cardioplegia was started at 200 ml/min, and the flow rate (Q) was adjusted to obtain a perfusion pressure (P) of 25-40 mmHg. Blood samples were collected at 13 different time points. The CPK-MB and TnI levels were measured on each sample. The use of the DBC was associated with increased P (P=0.03) at a lower Q (P=0.02). The CK-MB levels were significantly increased in both groups (P<0.0001). However, the use of the DBC was associated with lower levels of CK-MB (P=0.002). A similar trend was observed for the TnI levels (peak 5.1+/-1.8 ng/ml vs. 8.7+/-5 ng/ml, P=0.11). Occlusion of the coronary sinus ostium improved the hemodynamic efficiency of the RC, and this resulted in reduced perioperative ischemic myocardial damage. |
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Authors:
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Alfredogiuseppe Cerillo; Simona Storti; Dorela Haxhiademi; Marco Solinas; Paolo Del Sarto; Pier Andrea Farneti; Aldo Clerico; Mattia Glauber |
Publication Detail:
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Type: Journal Article Date: 2006-03-02 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 5 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2006 Jun |
Date Detail:
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Created Date: 2007-08-02 Completed Date: 2007-08-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 289-93 Citation Subset: - |
Affiliation:
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Operative Unit of Adult Cardiac Surgery, Ospedale G. Pasquinucci, Institute of Clinical Physiology, The National Research Council, Via Aurelia Sud, 54100 Massa, Italy. Cerillo@ifc.cnr.it |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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