Document Detail


The dose-response relationships of dipivalyl epinephrine in open-angle glaucoma.
MedLine Citation:
PMID:  305728     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The intraocular pressure responses of topically applied dipivalyl epinephrine (DPE: 0.025, 0.1, and 0.25%) were investigated in three series of open angle glaucoma patients in a double blind study. IOP responses were compared intra-individually with the effects of 1% epinephrine hydrochloride. 0.1% DPE gave an IOP reduction similar to that of 1% epinephrine-HCl. The change in IOP was less with 0.025% DPE and statistically significantly greater with 0.25% DPE when compared with the conventional epinephrine preparation. The clinical advantages of the 'pro drug' DPE are pointed out.
Authors:
G K Krieglstein; W Leydhecker
Related Documents :
1118568 - Ocular complications of orbital venography.
3132868 - Intranasal nitroglycerin and intraocular pressure during general anesthesia.
6767468 - "minified" goldmann applanating prism for tonometry in monkeys and humans.
17224758 - Travoprost 0.004% with and without benzalkonium chloride: a comparison of safety and ef...
1904968 - Differential effects of cyclooxygenase inhibitors on the cardiovascular response to hyp...
19798158 - Measurements of the hydrogen-induced and self-pressure-induced shift of h(2)o absorptio...
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology     Volume:  205     ISSN:  0065-6100     ISO Abbreviation:  Albrecht Von Graefes Arch Klin Exp Ophthalmol     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-05-08     Completed Date:  1978-05-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0044637     Medline TA:  Albrecht Von Graefes Arch Klin Exp Ophthalmol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  141-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Dose-Response Relationship, Drug
Epinephrine / administration & dosage,  pharmacology*,  therapeutic use
Glaucoma / drug therapy
Humans
Intraocular Pressure / drug effects
Chemical
Reg. No./Substance:
51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mycosis fungoides-like cells. Their presence in a case of pityriasic dermatitis with a comment on th...
Next Document:  The macular fatty degeneration of the peripheral retina a variety of the snail track degeneration (a...