Document Detail


The dose of house dust mite antigen (P1) inhaled by infants aged one month.
MedLine Citation:
PMID:  6638616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A survey of the habitats occupied by 12 infants of one month of age revealed that approximately 10% of their day was spent in conditions of potential exposure to the major (P1) allergen of the house dust mite, Dermatophagoides pteronyssinus. A respiratory pump which reproduced the minute ventilation of an infant was placed in representative infant habitats. The P1 allergen trapped by the filter in this pump was measured as an estimate of infants' allergen intake. Detectable P1 intake was only present when there was active air disturbance (bed making and vacuuming). The average P1 intake was approximately 3 ng P1/24 hours. Comparison of this P1 intake with that which sensitizes in other situations suggests that it is usually inadequate to sensitize infants.
Authors:
F Carswell; J Clark; P Robinson; T A Platts-Mills
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of allergy     Volume:  51     ISSN:  0003-4738     ISO Abbreviation:  Ann Allergy     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372346     Medline TA:  Ann Allergy     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  539-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Allergens*
Asthma / immunology*
Dose-Response Relationship, Immunologic
Dust
Environmental Exposure
Humans
Infant
Mites
Chemical
Reg. No./Substance:
0/Allergens; 0/Dust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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