Document Detail


A dopamine-secreting pheochromocytoma.
MedLine Citation:
PMID:  11206726     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe a patient with pheochromocytoma, which secretes dopamine. He was admitted to hospital because of chronic diarrhea. After surgical resection of the tumor, dramatic cessation of the diarrhea and blood pressure elevation were observed. Decreased expression of dopamine beta-hydroxylase in the tumor was considered a possible mechanism of producing a pathophysiological concentration of dopamine. This case shows that excessive excretion of dopamine, a vasodilative hormone, may affect blood pressure.
Authors:
K Yasunari; M Kohno; M Minami; H Kano; M Ohhira; K Nakamura; J Yoshikawa
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cardiovascular pharmacology     Volume:  36 Suppl 2     ISSN:  0160-2446     ISO Abbreviation:  J. Cardiovasc. Pharmacol.     Publication Date:  2000  
Date Detail:
Created Date:  2001-02-06     Completed Date:  2001-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7902492     Medline TA:  J Cardiovasc Pharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S75-7     Citation Subset:  IM    
Affiliation:
First Department of Internal Medicine, Osaka City University Medical School, Japan. yasunari@osaka.med.or.jp
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Neoplasms / secretion*
Aged
Catecholamines / blood
Dopamine / secretion*
Dopamine beta-Hydroxylase / metabolism
Humans
Male
Pheochromocytoma / secretion*
Chemical
Reg. No./Substance:
0/Catecholamines; EC 1.14.17.1/Dopamine beta-Hydroxylase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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